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Redbeard's avatar

Lately I have been looking into the connections between various theories of personality and various theories of how the brain works to try and come up with a new over-simplified way of understanding the connection. One potentially useful binary is the connection between local and global processing in the brain.

For example, if you squint just right you see that men tend to have more local processing power and woman have more global connectivity in their brains. If you squint even harder you might find that autism kind of looks like an over-emphasis on local processing and schizophrenia almost looks like too much global connectivity.

But this is all about the connectome...would your characterize the transcriptome as relating more to local or global computing?

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Orion Marino's avatar

Reminds me of the stories about personality shifts post organ transplantation. A cursory look at some papers and it doesnt look like the research is robust yet, but perhaps personality is conserved and transferred as a result of transcriptome memory. Even beyond that I know there are ongoing efforts by some researchers to bridge GRN research with psychotherapeutic modalities. Thanks for the article.

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